EFEK ANTIINFLAMASI EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium guajava Linn.) PADA TIKUS PUTIH JANTAN GALUR WISTAR. Article · January The guava has white flesh and not-perfectly-round shaped that resembles a crystal and seedless. Perbaikan Kualitas Buah Jambu Biji (Psidium guajava L.) Kultivar Kristal .. Budidaya Jambu Biji. REGENERASI BEBERAPA EKSPLAN TANAMAN JAMBU BIJI (Psidium guajava L.) PADA Skripsi Departemen Budidaya Pertanian Fakultas Pertanian, Institut.
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Chronic degenerative diseases have reached epidemic proportions in industrialized and developing countries. Many studies have shown that plant can be helpful to prevent or treat diseases.
Journal of Aquaculture Management and Technology
It is popularly known as guava and has been used traditionally as a medicinal plant throughout the world for a number of ailments. The aim of this review is to present some chemical compounds in P.
The main constituents of guava leaves are phenolic compounds, isoflavonoids, gallic acid, catechin, epicathechin, rutin, naringeninkaempferol. The seeds, skin and barks possess glycosids, carotenoids and phenolic compounds. All parts of the plant have been used for different purposes: Furthermore leaves, seeds and peel are treated as wastes by the food processing industry and are discarded, so their use may reduce the disposal of these parts of guava as pollutants.
Ann Jose ankara escort. Home Publications Conferences Register Contact. Guidelines Upcoming Special Issues. Review Article Open Access. Sandra Maria Barbalho Av. A Plant of Multipurpose Medicinal Applications. Med Aromat Plants 1: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Select your language of interest to view the total content in your interested language. Can’t read the image? Agri and Aquaculture Journals Dr. Pharmaceutical Sciences Journals Ann Jose ankara escort. Studies have demonstrated that the consumption of fruits, vegetables and seeds can be helpful to prevent the risk factors of many diseases due to the bioactive compounds. Many plants have been used for the purpose of reducing risk factors associated with the occurrence of chronic disorders and for many other purposes [ 3 – 8 ].
It is popularly known as guava family Myrtaceae and has been used traditionally as a medicinal plant throughout the world for a number of ailments. There are two most common varieties of guava: All parts of this tree, including fruits, leaves, bark, and roots, have been used for treating stomachache and diarrhea in many countries. Leaves, pulp and seeds are used to treat respiratory and gastrointestinal disorders, and as an antispasmodic, anti-inflammatory, as a cough sedative, anti-diarrheic, in the management of hypertension, obesity and in the control of diabetes mellitus.
It also possesses anticancer properties [ 11 ]. The seeds are used as antimicrobial, gastrointestinalanti-allergic and anticarcinogenic activity [ 12 – 15 ].
As result of the fruit process there is a discard of the leaves, seeds, part of the peel and pulp fraction not separated in the physical depulping process [ 9101617 ].
The high cost of pharmaceutical medications conduces to the search for alternative medicines to treat many ailments.
In view of this, studies are necessary to confirm the effects of medicinal plants. The aim of this review is to show that several studies have demonstrated the presence of many different chemical compounds in P.
The main constituents of guava are vitamins, taninsphenolic compounds, flavonoids, essential oils, sesquiterpene alcohols and triterpenoid acids. These and other compounds are related to many health effects of guava [ 10 ]. Some authors have found high concentrations of carotenoids beta-carotene, lycopeneand beta-cryptoxanthinvitamin C and polyphenols in guava pulp [ 18 – 20 ].
Lycopene has been correlated with the prevention of cardiovascular damage because of its positive effects on dyslipidemia pssidium 2122 ].
Ascorbic acid is recognized for its important antioxidant effects [ 23 – 25 ]. Ursolic acid and other triterpenoids are associated with anti-cancer properties [ 27 ].
Factsheet – Psidium guajava (Guava)
Benzophenone glycosides have inhibitory effect on triglycerides accumulation [ 29 ]. The antioxidant properties of the guava pulp can be related to anti-cancer effects [ 15 ]. Lyophilized pulp of P. Guava leaf extract has analgesic, anti-inflammatoryantimicrobial, hepatoprotective and antioxidant activities. These effects are probably due to the presence of phenolic compounds [ 1134 – 39 ].
Wu et al [ 42 ], Melo et al. Studies have shown that gallic acid, catechin, and epicatechin inhibit pancreatic cholesterol esterase, which decreases cholesterol levels. Catechins are important as a preventive treatment for diabetes type 2 and obesity. Quercetin has been associated to decreased mortality from heart disease and decreased incidence of stroke. Quercetin presents hypocholesterolemic and antioxidant activity. Rutin is effective in the inhibition of triglyceride accumulation in adipocytes.
Naringenin and kaempferol can promote moderate cytostatic activity against all cell lines and kaempferol can be useful as anti cancer [ 44 – 49 ]. Betulinic acid and lupeol can be used in the treatment of diabetes, cardiovascular desease, obesity and atherosclerosis [ 54 ].
Psiguadials A and B, two novel sesquiterpenoid-diphenylmethane meroterpenoids with unusual skeletons, along with a pair of known epimers, psidial A and guajadial. Guaijaverin has high potential antiplaque agent by inhibiting the growth of the Streptococcus mutans.
Avicularin and guaijaverin work as urease inhibitors against Helicobacter pylori urease [ 5758 ]. Guava aqueous leaf extract showed anti-trypanosomal properties in rats experimentally infected with Trypanosoma brucei brucei [ 60 ]. They concluded that this plant offers potential for controlling epidemics of cholera. The antimicrobial activity can be linked to the presence of flavonoids extracted from guava leaves [ 6465 ].
Deguchi and Miyazaki [ 66 ] reported that guava leaves infusion not only reduced postprandial glycemia and improved hyperinsulinemia in murine models but also contributed to reduce hypercholesterolemia, hypertriglyceridemia and hypoadiponectinemia in the animals of their study. Rutin and kaempferol found in guava leaves are compounds related to the decrease of HMG-CoA reductase activity in hepatic tissue and improve lipid profiles [ 67 ].
Several studies have shown that aqueous extract of Psidium guajava contains components with LDL-c antiglycation activity, suggesting its contribution to the prevention of neurodegenerative and cardiovascular diseases [ 6970 ]. Other studies have found cardioprotective effects of aqueous extract of P. Ojewole [ 72 ] identified the presence of phenolic compounds in the leaves demonstrating their hypoglycemic and hypotensive effects on diabetic rats treated with aqueous leaf extract.
Singh and Marar [ 74 ] studied the effects of Psidium guajava leaves on the inhibition of the activity intestinal glycosidases related with postprandial hyperglycemia, suggesting its use for the treatment of individuals with type 2 diabetes.
Psidium guajava – Wikipedia
Other studies have demonstrated that guava leaf and peel extracts also had hypoglycemic effects on experimental models drug-induced to severe conditions of diabetes [ 177576 ]. The Psiguadials A, B and psisium isolated by Shao et al. Dutta and Das [ 77 ] identified significant anti-inflammatory activity of the ethanol extract of guava leaves in experimental models, while Kawakami et al.
Guava budding leaves aqueous extract possesses an extremely high content of polyphenolic and isoflavonoids and suppresses the cell migration and the angiogenesis. In view of this, clinically it has the potential to be used as an adjuvant anti-cancer chemopreventive [ 7980 ]. Roy and Das [ 81 ] studied the hepatoprotective activity of different extracts of P.
The effects were compared with a known hepatoprotective agent and observed that the best effects came from guava methanolic leaf extract that significantly reduced the elevated serum levels of enzymes aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and bilirubin.
This molecule is a product of a defective genetic code of hemoglobin molecule and is prone to deoxygenation-induced polymerization and has low insolubility. The development of chemical modification agents that reduce the tendency of sickle cell hemoglobin molecule to aggregate represents an important chemotherapeutic goal [ 82 ]. Guava extract leaves can be responsible for membrane stabilizing effect on sickle erythrocytes that are susceptible to endogenous free radical-mediated oxidative damage.
This effect can be attributed to the flavonoids, triterpenoids and host of other secondary plant metabolites [ 83 ]. Methanol extracts of the leaves can also be useful in the treatment of gastric ulcer disorders possibly due to the presence of volatile oil, flavonoids and saponins [ 85 ].
Methanolic extract of guava leaves can exhibit wound healing effects and this property can be explained by the presence of tannins and flavonoids [ 8687 ]. Guava leaves extract also can show anti cough effects as shown by Jaiarj et al [ 88 ]. As told before, the fruit process results in the discard of the leaves, seeds, part of the peel and pulp.
Some studies showed the presence of total phenolic compounds in the agroindustrial wastes seeds, skin and pulp of guava, confirming its antioxidant activity [ 163272 ].
Leaves, seeds and peels of fruits have significant proportions of bioactive compounds with beneficial physiological and metabolic properties. Its antioxidants can control body weight and biochemical variables like glycemia, dyslipidemia, hypertension and other risks of cardiovascular diseases. The antioxidant properties of the guava seeds extracts can be associated to anti-cancer effects on both hematological and solid neoplasms and the psiidium properties of the guava peel can be related to anti-cancer effects.
Seeds exhibit antimicrobial, gastrointestinal and anticarcinogenic activities probably due to the presence of phenolic glycosides in the composition [ 1293 ]. These animals significantly increased HDL-c levels. Psidium guajava stem-bark extract can be used to budidayaa malaria because it presents antiplasmodial activities possibly due to the presence of anthraquinones, flavonoids, seccoirridoids and terpenoids. Table 1 presents some compounds in tuajava leaves, pulp, seed, skin and bark and their pharmacological effects.
Many researchers have been demonstrating the presence of a wide variety of bioactive compounds in the leaf, seed and bark of Psidium guajava that are capable of showing beneficial effects on human health. If we consider that chronic degenerative diseases have reached epidemic proportions in many countries and increase the socio-economic burden for the public health system, it is necessary to find non-allopathic alternatives that minimize risk factors of these diseases and help in the treatment.
Furthermore, population consumes medicinal plants also to treat other kind or diseases because of high costs of allopathic medications. The studies using P. Nevertheless we should emphasize the importance of experimental and clinical studies involving more specific factors related to the bioavailability of the compounds, as well as the effective and safe doses to be used by individuals for the prevention and treatment of various disorders.
Part 1-etiology, classification, and pathogenesis. J Altern Complement Med Evid Based Complement Alternat Med: Indian J Physiol Pharmacol J Med Food Psidiuum Chem Guanava J Agric Food Chem Arch Latinoam Nutr